FIG 3. Phase-contrast micrograph of BAECs on PS surface patterned by ion implantation (original magnification, x100; diameter of a circle, 100 µm).

A, Day 1, no endothelial proliferation was observed on either protein-coated only (area A) or ion-implanted protein-coated (area B) surface.

B, Day 5, areas A and B demonstrated uniform proliferation of the BAECs.

C, Day 5, Post-trypsin treatment at 2 hours. Note most of BAECs were strongly attached on the ion-implanted circular area. Almost no BAECs were observed on surface coated with collagen only.