FIG 6. Patients 18 and 19: late-onset GLD.

A, Axial T2-weighted image (2700/90/1) in patient 19 shows asymmetric increased signal intensity in the right coronal radiata pyramidal tract (straight arrow) and the right parietooccipital white matter (curved arrow).

B, Axial T2-weighted image (2700/90/1) in patient 18 (monozygotic twin of patient 19) shows asymmetric increased signal in the left corona radiata pyramidal tract (straight arrow) and bilateral increased signal in the parietooccipital white matter (curved arrows).