FIG 2. Axial T2-weighted RARE (3300/98/1) (A), PD-weighted RARE (3300/16/1) (B), T1-weighted CSE (768/14/2) (C), and fast FLAIR (9500/119/1) (D) images of the brain of a patient with secondary progressive MS. On dual-echo RARE images (A and B), confluent, hyperintense lesions are visible in the posterior periventricular regions, and some of them appear as black holes on the corresponding T1-weighted image (C). On the fast FLAIR image (D), within the left periventricular confluent lesion, hypointense areas are visible and correspond well to T1-weighted black holes (C)