FIG 5. Case 10 at 5 months of age.

A–C, Axial (A), coronal (B), and sagittal (C) SPECT scans show diffuse cortical activity, with prominent activity in parietal cortex. Relative activity in the thalami, brain stem, and cerebellum subsided around this stage.

D, Axial SE (600/15) MR image shows absence of myelination in the frontal white matter.