FIG 1. MR and clinical score graphs. The MR and clinical scores are presented for animals HWM-1 (A), HWM-2 (B), MP4–1 (C), and MP4–2 (D). MR scans and histologic images are presented in figures 2–5. The dynamic nature of the MR-revealed changes is demonstrated by the changes in MR scores. These graphs show the lack of a direct correlation between clinical disease and lesion activity in the brain, particularly in the relapsing-remitting animals (MP4–1, MP4–2). More detailed information on the clinical and MR scores is presented in Tables 3–5