FIG 3. A–E, Cross-sectional T1-weighted (800/22/6) (A) and T2-weighted (2000/80/4) (B) images of rat spinal cord 4 weeks after injection show a cystic lesion within the spinal cord (arrow), hypointense on the T1-weighted image and hyperintense on the T2-weighted image. A linear area of low signal intensity on both the T1- and T2-weighted images is seen within the dorsal gray matter (arrowhead), representing neuronal degeneration, gliosis, and scarring along the injection tract. Corresponding ADC maps in the read (C) and slice-select (D) axes show this cystic lesion (arrow) to be hyperintense in both axes. The cystic lesion seen on the MR images corresponds to the cyst (C) seen in the histopathologic specimen (E), and the glial scarring seen on the conventional MR images is marked with an arrowhead; note the decreased amount of debris within the cyst as compared with the cavities seen in figure 2E