FIG 2. Data from a representative hypoxic node in patient 7.

A, T2-weighted image (3000/85/2) shows the location of the PRESS box.

B, Histogram of oxygenation measurements. The median pO₂ value is 1.3 mm Hg, which is very suggestive of hypoxia.

C, Uncoupled (Cycle 1 + Cycle 2).

D, Coupled (Cycle 1—Cycle 2).

E, Error spectra acquired with MRS parameters of 2000/144/256. The Cho:Cr ratio is 1.3.