FIG 1. A, MR signal versus time curves for the empirical model ROI. The signal was taken from an ROI of all nonenhancing pixels from the hemisphere contralateral to the abnormality.

B, Time courses for the empirical model of vascular concentration (with error bars) and for the associated tissue concentration. The intravascular concentration model was obtained from the time curve for nonenhancing pixels shown in A. The model of contrast agent concentration in the tissue was calculated from the empirical model of the intravascular concentration.