FIG 1. Case 1: 54-year-old woman who underwent renal transplantation and immunosuppressive therapy with FK 506.

A, Contrast-enhanced axial CT scan obtained at the onset of symptoms shows subcortical bilateral parietal hypodensities (arrows).

B and C, Axial T2-weighted MR images 12 hours later show diffuse cortical and white matter hyperintensities involving the bilateral frontal and parietal lobes (B). Involvement of right thalamus (black arrow), white matter, and both occipital lobes is also observed (white arrows) (C).

D and E, Follow-up MR studies 3 weeks later show complete resolution of the initial lesions. Axial T2-weighted image at the same position as B (D) shows no abnormalities. Axial T1-weighted unenhanced image (E) shows curvilinear areas of hyperintensity of superficial cortical layers in the parietal region (arrows).