FIG 3. Case 3: 18-year-old woman treated for acute lymphoid T leukemia with polychemotherapy, including vincristine and methotrexate.

A, Axial contrast-enhanced CT scan obtained at the onset of neurologic symptoms shows right parietal white matter hypodensity (black arrows) and subtle patchy hypodensities in the frontal white matter (white arrows).

B and C, MR study performed the same day. Axial T2-weighted image in the posterior fossa (B) shows diffuse bilateral cerebellar lesions. Axial T2-weighted image in the frontoparietal lobes (C) shows thickened cortex of both frontal and parietal lobes with parietal white matter involvement.

D and E, MR study 11 days later. T2-weighted image in the frontoparietal region (D) shows complete resolution of the initial lesions. Corresponding axial noncontrast T1-weighted image (E) shows laminar hyperintensities in the bilateral frontal cortex (arrows).