FIG 2. Case 11: A typical case in which the spectroscopic voxel is homogeneous without contrast enhancement.

A, Contrast-enhanced T1-weighted MR image shows the spectroscopic voxel (square) filled with unenhanced homogeneous tumor.

B, Proton spectrum obtained from the region indicated in A shows a Cho value of 2.06.

C, Photomicrograph of the resected tumor indicates anaplastic astrocytoma (grade 3) (hematoxylin-eosin, original magnification x100).

D, Photomicrograph of Ki-67 staining of the same tumor specimen shows a Ki-67 labeling index of 3.10% (original magnification x100).