FIG 4. Infant born at 37 3/7 weeks.

A–D, Coronal and parasagittal sonograms (A) at a PCA of 38 2/7 weeks show a diffuse increased echogenicity throughout the white matter and basal ganglia with an inhomogeneous, partly precystic aspect in the frontal region. Proton density–weighted (B), T2-weighted (C), and inversion recovery (D) MR images in the axial plane show large areas of high signal on the proton density–weighted image (B) and combined high and low signal changes on the T2-weighted and inversion recovery images throughout the white matter (C, D) and basal ganglia (D). In comparison with sonograms, MR images show more extensive, small, partly cystic and partly precystic periventricular lesions in the frontal and parietal region, with signal intensities identical or close to CSF (B–D). The hemorrhagic ischemic areas correspond to the large cystic lesions detected at autopsy performed 4 days later.