FIG. 1. Axial nonenhanced CT sections obtained 24 h after seizure in a patient (case 4) who was conditioned for transplantation with cyclophosphamide and TBI. She had a new-onset seizure 23 d after transplantation. At the onset of toxic reaction, she had grade 3 BMT-related TM, and her CsA level was within the normal therapeutic range. The initial head CT study obtained on the day of the seizure was normal. Her baseline blood pressure was 92/52 mm Hg but increased to 230/130 mm Hg at the time of toxic reaction and initial CT.

A, Image at the level of lateral ventricles shows edema in the corpus callosum (arrow).

B, Image at the level of the sentrum semiovale shows extensive areas of white matter edema in the parietal region bilaterally (arrow).