FIG 1. The location of selected ROIs. Four ROIs were selected in the lesional deep white matter and three in the lesional centrum semiovale. Although this figure shows that ROIs were placed only on MTR maps and CBF images, actually the same ROIs were selected on T2-weighted images and other PET scans (CMRO₂ and OEF images). PET scans were registered to the MR images of each subject. Circular ROIs were placed in right and left symmetrical locations, so that the AI could be calculated