FIG 6. A 47-year-old man with glioblastoma.

A, Contrast-enhanced T1-weighted image at 3700/96/1 (TR/TE/excitation).

B and C, SE-EPI at 2000/97/1 (B) and GE-EPI at 2000/46/1 (C). Tumor rCBV is higher than that of gray and white matter obtained with the two techniques, but the hypervascular area of the tumor (B and C, arrow) is more conspicuous with GE-EPI.

D and E, The R2* and R2 curves during the transit of the contrast material through the gray and white matter regions of the brain and the two areas within the tumor that were measured using each of the SE- and GE-EPI techniques, respectively. The curves with white and black circles represent the tumor; the curves with squares and triangles represent the gray and white matter, respectively. Interestingly, the susceptibility effects within the tumor did not completely disappear after the first pass of the contrast medium on the GE-EPI image (D, arrow), whereas they almost completely disappeared on the SE-EPI image (E, arrow).