FIG 3. Composite, axial T1-weighted image and fMR imaging activation map at the level of the primary visual cortex in a patient with MS at three luminance contrast levels: (A) lowest (baseline), (B) intermediate, (C) highest. Activation in the primary visual cortex is shown in red and yellow. There is low-level fMR imaging activation in A, no significant change in activation in B, and prominent activation in C.