FIG 1. Images used in volume determination.

A, Coronal T2-weighted MR image.

B, Coronal intermediate-weighted MR image.

C, Segmentation image from A and B.

D, Feature space showing separation of CSF (blue), white matter (khaki), and gray matter (tan).

E, Close-up segmented image of the right temporal lobe depicts the hippocampus and five temporal gyri.

F, The red line indicates the length of WM from the base of the superior temporal sulcus to the base of rhinal sulcus and defines the temporal stem measurement. The linear distance (in centimeters) provided the basis for this measure, summed across all sections.