FIG 2. Comparison of patient and control spectra in the group aged 2 years or younger.

A, Proton MR spectrum in left frontal white matter in a 1.5-year-old control subject demonstrates an NAA/Cr ratio of 2.12 and a Cho/Cr ratio of 1.81.

B, Proton MR spectrum from a voxel placed in the subcortical white matter of the left frontal lobe in a 1.5-year-old patient with mild developmental delay demonstrates a slightly higher Cho peak and higher Cho/Cr ratio of 2.01. This value, however, was not significantly different than that in the 1.5-year-old control subject. Likewise, the NAA peak is slightly lower and the NAA/Cr ratio of 1.94 is less than that in the control subject but not significantly different.