FIG 2. T2 metastasis in a 36-year-old female patient with invasive ductal carcinoma of the breast.

A, T1-weighted MR image (583/12) obtained before radiation therapy shows focal hypointense metastatic lesion (arrow) in right posterior portion of the vertebral body.

B, T2-weighted MR image (3800/128) obtained before radiation therapy shows focal hypointense metastatic lesion (arrow) in right posterior portion of the vertebral body.

C, Diffusion-weighted MR image (TR, 21.6; diffusion pulse length, 2 ms) obtained before radiation therapy reveals hyperintensity (arrows) relative to normal bone marrow.

D, Follow-up T1-weighted MR image shows persistent hypointense signal (arrow).

E, T2-weighted MR image reveals hyperintense signal (arrow).

F, Diffusion-weighted MR image shows hypointensity (arrow) relative to normal bone marrow 2 months after therapy.

G, Diffusion-weighted MR image obtained 3 months after therapy shows more hypointense change (arrows). Longer follow-up diffusion-weighted MR image shows more hypointense change in metastasis to the spine with clinical improvement.