FIG 3. Axial T2-weighted MR images (3000/80/2 [TR/TE/NEX]) in a 22-year-old patient who had abused thinner for 11 years.

A, Symmetric hypointensity is present in the thalami (arrows). Symmetric hyperintensity exists in the posterior limbs of the internal capsule (arrowheads).

B, At the level of the posterior fossa, generalized increased signal intensity in the cerebellar white matter emphasizes the dentate nucleus (arrowheads).

C, At the level of midbrain, red nuclei (arrows) and substantia nigra (arrowheads) are hypointense.

D, Diffuse high-signal-intensity in the centrum semiovale causes loss of gray matter-white matter differentiation. Gray matter-white matter differentiation is preserved only in the subcortical-frontal white matter (arrow). The cerebral sulci are mildly dilated.