FIG 3. Comparison of infarct diffusibility with time.

A, Scatterplot of relative ADC versus log hours from symptom onset. The line represents the linear regression that fit the data. The line intercepts 1 (ie, infarcts had pseudonormal ADC values) at a time corresponding to 9.8 days.

B, Scatterplot of log of the ratio of lesion signal intensity on the image with b = 1000 s/mm² to the lesion signal intensity on the image with b = 0 s/mm². The component of infarct signal intensity due to the ADC effect (SI_RAT) is the ratio of SI_{DWI lesion}/SI_{b0 lesion} to SI_{DWI control}/SI_{b0 control}. Decreased ADC contributes in a positive way to infarct signal intensity during the first 10 days after symptom onset. Increased lesion ADC contributes in a negative way to infarct signal intensity thereafter. The thick line represents the best fit for the study data. The thin lines represent the 95% confidence limits for this fitted curve.