FIG 9. 60-year-old woman with glioblastoma.

A and B, Contrast-enhanced T1-weighted (A) and rCBV (B) MR images show a heterogeneously enhancing anterior right temporal lobe mass. The entire mass, including regions of both minimal and maximal contrast enhancement, demonstrates homogeneously increased rCBV, consistent with biopsy proved high-grade glioma (arrow in B). The elevated blood volume extends even to tumor foci without significant contrast enhancement.