FIG 2. Serial axial T2-weighted MR images from case 4 obtained (A) 3 months, (B) 5 months, (C) 7 months, (D) 9 months, (E) 12 months, and (F) 18 months after onset of symptoms. Slight hyperintensities are shown around the lateral ventricles (B, arrows) 5 months after the onset. The periventricular hyperintensities are gradually extending to the deep and subcortical white matter in parallel with cortical atrophy (C–F).