FIG 1. Statistical maps showing the relative decrease of rCBF in men with AD compared with that in control subjects (top) and in women with AD compared with that in control subjects (bottom).

Although both patient groups show a notable decrease of rCBF in the parietotemporal lobes, posterior cingulate cortex, cinguloparietal transitional area, and frontal association cortices, men have a more severe reduction of rCBF in the parietal lobe and posterior cingulate cortex, and women have reduced rCBF in additional areas, including the frontal lobe and medial temporal regions. The color of the outer contour corresponds to a Z score of 7.