Click on image to view larger version.



FIG 1. Spatial and temporal evolution of injury after pilocarpine-induced seizures. ROIs—piriform cortex (PC) and amygdala (A)—are defined on the first control image. Increased signal intensity in the piriform cortex and amygdala returned to control levels by 7 days. Diffusion maps were generated from unweighted (b = 0 s/cm2) and weighted (b = 30,000 s/cm2) images. Note increased signal intensity in the piriform cortex (arrows); corresponding hypointensities are seen on ADC maps, particularly at 12 hours (arrows).