FIG 6. GFAP-stained sections of the piriform cortex-amygdala complex.

A, Control section reveals a uniform and diffuse staining pattern.

B, At 12 hours, section shows increased staining properties, particularly at the intersection of layer I and II (arrows).

C, This staining pattern was exacerbated at 24 hours, with increased vacuolization in layers II–IV (arrows).

D, Seven days after seizures, GFAP staining is substantially increased in layers I, II and IV. However, layer III (region bounded by dotted lines) is virtually devoid of GFAP staining but stains with OX42, an immunologic stain for microglia (data not shown). G indicates gliosis.