FIG 2. Histograms of pixel values for ADC ratio (left) and signal intensity ratio (right). Histogram for ADC ratio shows a leftward shift of the curve in ROI_IG (B) compared with the curve for normal tissue, or ROI_CONTIG (C). There is further a leftward shift of ADC ratios in ROI_{DW image CORE} (A) compared with that in infarct growth (B). Histogram of signal intensity ratio shows similar patterns (with a rightward shift). Pixel values for infarct growth and normal tissue significantly overlap. The overlap was greater with the ADC ratio than with the signal intensity ratio.