FIG 3. Scattergrams showing the relationships between histologic grade and median values of K^trans, K^trans (95%), CBV, and CBV (95%). Individual cases are indicated by circles, multiple cases are represented by the addition of "petals" to the glyph with the number of petals representing the number of cases. Lines indicate the optimal linear regression fit for the data and the 95th percentile confidence limits for the regression fit for the entire dataset. The correlation between grade and the median values of each of the parametric variables is significant (K^trans, K^trans [95%], CBV, and CBV [95%]; P < .01).