FIG 7. Abnormal thalamic appearance in sCJD.

A, DWI in a 41-year-old man shows symmetric hyperintensity in bilateral caudate nuclei and putamina and medial and posterior thalami (double hockey stick). No definite neocortical abnormality is seen. Cingulate cortex and insular cortices are mildly hyperintense but likely within normal limits.

B, Axial DWI in a 59-year-old woman shows abnormal hyperintensity in bilateral medial thalami and pulvinar. Left insular cortex (arrows) was thought to be definitely abnormal, and right, possibly abnormal. Caudate nuclei and putamina are spared.