Fig 3. Left thalamic/posterior frontal GBM (WHO grade IV) in a 63-year-old man. Upper panel, Left, Transaxial contrast-enhanced SPGR image demonstrates an enhancing left dorsolateral thalamic and posterior frontal lobe tumor (arrow). Middle and Right, Transaxial T2-weighted image (middle) and FLAIR (right) show moderate degree of surrounding edema (arrowheads). Lower panel, Left, Transaxial ssT1 K^trans map demonstrates a rim of increased permeability (arrow). Middle, Transaxial fpT2* K^trans color map overlayed onto SPGR image also shows a rim of increased permeability. Right, Transaxial fpT2* rCBV color map overlayed onto SPGR image demonstrates similar rim shape of increased blood volume but more focused on the medial aspect of the tumor (arrow).