Fig 1. Neuronal activations associated with the initiation and maintenance of EPT in a 41-year-old patient. Peak activation assessed by fMRI is present in the putamen bilaterally (A). Additional activation is found in precentral gyrus bilaterally (B) and right superior temporal and angular gyrus (not shown). No focal activation could be observed in prefrontal motor cortex, the brain stem, or the cerebellum. The analysis is based on a fixed-effects GLM with statistical threshold of P < .01 (corrected Bonferroni) and spatial threshold of 500 mm³. Radiologic convention: right hemisphere is depicted on the left-hand side.