Fig 2. Case 2. A 71-year-old man with metastatic brain tumor located inside the right-sided S1.

A-1, Preoperative MR imaging displays heterogeneously enhancing tumor in the S1.

A-2, Postoperative MR imaging shows no residual tumor in the S1.

B, fMRI images activated by left hand clenching (B, orange) and right hand clenching (B, blue) before surgery.

C, fMRI images activated by left hand clenching (orange) and right hand clenching (blue) after surgery. Left hand clenching (orange area in B) activated the contralateral M1 and S1 areas separately before surgery and (orange area in C) activated the large area of the contralateral M1 and S1, and contralateral supplementary motor area after surgery.