Fig 2. A 2.3-year-old boy (patient 12) with severe sequelae.

A, Axial T1-weighted imaging (449 ms/12 ms, TR/TE) shows sharply marginated hypointensity in the cerebellum (arrowheads).

B, Axial T1-weighted imaging shows hyperintensity in the thalami (arrows) and the right occipital lobe (double arrows). Sharply marginated hypointense areas are found in the cerebral white matter (arrowheads) and the internal capsules (small arrowheads). The lentiform nuclei also show mixed intensity (double arrowheads).

C and D, Coronal T2-weighted imaging show mixed intensity in the thalami (arrows), and hyperintensity in the cerebral white matter, internal capsules (small arrowheads), and the cerebellum (double arrowheads). There are 2 types of white matter lesions: those in the central white matter and internal capsules showing hyperintensity comparable with the CSF (arrowheads) and those in the subcortical regions being less hyperintense (double arrows).