Fig 1. Selected T2-weighted images, DWI, and ADC maps of patient 1. The axial views of the T2-weighted image (TR/TE, 3203/96.0 ms) of patient 1 show the symmetric hyperintense lesions in the pontine tegmenta (A) and the bilateral basal ganglia (B) at 6 years of age. DWI (b = 1000 s/mm²) displays the hyperintense lesions of the pontine tegmenta at 6 years (C) and 8 years of age (E). The ADC map at 6 years (D) and 8 years of age (F) was obtained from the DWI (C and E). In panels A and C–F, the pontes are shown with higher magnification (insets). Arrows indicate the hyperintense lesions on T2-weighted images and DWI.