Fig 2. Scatterplot of rCBV versus K^trans shows true low-grade gliomas as crosses and true high grade gliomas as black points. The figure demonstrates that rCBV and K^trans together are good predictors of glioma grade. The performance of the diagnostic model to predict high-grade tumors using both K^trans and Max rCBV when overall diagnostic accuracy is highest (sensitivity = 90.7%, specificity = 76.7%) is shown.