Fig 5. A–H, Glioblastoma multiforme (grade IV/IV). Top row, left to right.

A, Axial FLAIR image (TR/TE/TI, 9000/110/2500 ms) demonstrates a lesion with surrounding increased signal intensity in the left parietooccipital region.

B, Axial T1-weighted postcontrast image (TR/TE, 600/14 ms; 1 excitation) demonstrates heterogeneous contrast enhancement in keeping with a glioblastoma multiforme.

C, Gradient-echo axial DSC MR image (TR/TE, 1000/54 ms).

D, SD25 color map shows foci of increased permeability anteriorly in the lesion, which appears to "washout" on the axial postcontrast T1-weighted image (arrows), possibly indicating hyperpermeability during the first pass of contrast. The areas of enhancement more posteriorly may reflect more delayed permeability.

E–G, Bottom row (left to right). rCBV, CBV, and CBF maps demonstrate elevated rCBV, CBV, and CBF within the glioblastoma multiforme.

H, MTT map demonstrates some prolongation in MTT within the tumor.