Fig 2. Same as Fig 1, except that the average individual rates of WBNAA decline per year, R₂, were estimated for disease duration from FS, Y₂, as defined by Equations (2) and (5b). The vertical dotted lines at R₁ = 0 and 1.7 mmol/L/y partition the cohort into stable (), moderate (), and rapid () decline rates according to criteria defined in the text.²³