Fig 4. Abnormal peak height and percentage of signal intensity recovery maps in a GBM (A) and a breast cancer metastasis (B). The blue overlay represents an area of abnormal peak height (greater than twice the normal brain) and pink overlay depicts area of less than 50% signal intensity recovery of T2* relaxivity curve.

A, Top row, left frontal GBM in a 45-year-old man. Axial (2 left images) and coronal (2 right images) contrast-enhanced T1-weighted images show a large area of peak height abnormality (blue) but only a small area of less than 50% signal intensity recovery (arrow, pink), suggesting highly vascular but not permeable vessels.

B, Bottom row, left occipital breast cancer metastasis in a 62-year-old woman. Axial (2 left images) and coronal (2 right images) contrast-enhanced T1-weighted images demonstrate large areas of both abnormal peak height (blue) and less than 50% signal intensity recovery (pink), suggesting vascular but also highly permeable microvasculature of the metastatic tumor.