Fig 3. A, A representative LASER (TR/TE = 2200/46 ms) spectrum (including metabolite and macromolecule components) from 1 patient with low-grade glioma. The corresponding metabolite nulled macromolecule spectrum (B) is subtracted from a fully processed spectrum (A). C, The resultant spectrum after water removal demonstrates the efficacy of the macromolecule removal. D, A second dataset acquired in a different subject is also provided. Spectra have been line broadened by a 2-Hz Lorentzian filter for display.