Fig 1. T2-weighted MR, selected spectra, and metabolic images of Cho, Cr, NAA, and lactate (Lac) in a typical case of hypomyelination (Pelizaeus-Merzbacher disease). Spectral patterns from both white and gray matter show near-normal profiles, with a large NAA signal intensity and near-equal Cho and Cr. Bright signal at the corners of the metabolic images arises from residual lipid signals from the scalp. PPM indicates parts per million.