Fig 1. Whole-head WET (followed by a 13 [100-µs rectangular pulses with 2-ms interpulse delays at 3T] for a 90° readout) single-acquisition ¹H proton spectrum. Note the extreme lipid contamination from the bone marrow and subcutaneous adipose tissue distorting and obscuring the NAA signal intensity and confounding its quantification. Cho indicates choline; Cr, creatine.