Fig 3. Vascular low-pass filtering of neurovascular coupling. A, Data in the first column represent BOLD responses to a 6-Hz flashing radial checkerboard pattern turned ON and OFF at frequencies ranging from 0.01 to 0.5 Hz. Data in the second column represent BOLD responses to single flashes of 1 screen refresh duration (13 ms) of the same radial checkerboard pattern presented at frequencies ranging from 0.1 to 4 Hz. B, Peak-to-peak response for 1 period of the stimulus. Individual points plotted are responses from each subject of the amplitude of the BOLD response averaged across all cycles of stimulus presentation. Left and right hemifield responses are plotted as separate data points on the left and are averaged for each data point on the right. Error bars represent 1 standard error of the mean. C, Mean BOLD responses compared with baseline (blank screen stimulus), averaged across the entire trial for each frequency condition. Data points and error bars are as in Fig 3B.