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American Journal of Neuroradiology, Vol 13, Issue 3 976-980, Copyright © 1992 by American Society of Neuroradiology


ARTICLES

Bruton-type (congenital X-linked) agammaglobulinemia: MR imaging of unusual intracranial complications

EJ Lerner and LT Bilaniuk
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.

The authors describe two patients with Bruton-type agammaglobulinemia, their purpose being to indicate the spectrum of findings, clinical and imaging. MR in one patient revealed diffuse leptomeningeal enhancement in the brain and spine; in the second patient, a heterogeneous mass was seen that had broken through the basiocciput and displaced a cerebellar hemisphere. Awareness of the common and unusual CNS manifestations of this disease can impact clinical management.


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