AJDRAJNR - American Journal of Neuroradiology

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chien, D.
Right arrow Articles by Rosen, B. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chien, D.
Right arrow Articles by Rosen, B. R.

American Journal of Neuroradiology, Vol 13, Issue 4 1097-1102, Copyright © 1992 by American Society of Neuroradiology

ARTICLES

MR diffusion imaging of cerebral infarction in humans

D Chien, KK Kwong, DR Gress, FS Buonanno, RB Buxton and BR Rosen
VA Medical Center, San Francisco, CA.

PURPOSE: MR diffusion imaging was performed to investigate changes in water diffusion in patients with cerebral infarction. METHODS: Diffusion maps of the apparent diffusion coefficient (ADC) were created to show local water mobility in the brain tissue in 15 patients. These ADC maps were compared with conventional T2-weighted images. RESULTS: Distinct subregions with different water diffusions were detected, even when the infarcted area appeared homogeneous on a T2-weighted image. The results also show that stroke lesions of the same age can have very different water diffusions. A trend towards an increasing diffusion coefficient in a lesion during the first several days following an acute event was observed in a group of patients imaged at multiple timepoints. CONCLUSION: The measurement of diffusion coefficients in vivo now offers an opportunity for greater understanding of the biophysical changes that occur during the evolution of infarction in humans.


This article has been cited by other articles:


Home page
 Am. J. Neuroradiol.Home page
P. Mukherjee, J.I. Berman, S.W. Chung, C.P. Hess, and R.G. Henry
Diffusion Tensor MR Imaging and Fiber Tractography: Theoretic Underpinnings
AJNR Am. J. Neuroradiol., April 1, 2008; 29(4): 632 - 641.
[Abstract] [Full Text] [PDF]

Home page
 J. Neuropsychiatry Clin. Neurosi.Home page
M. Alemdar, P. Iseri, M. Selekler, F. Budak, A. Demirci, and S. S. Komsuoglu
MELAS Presented With Status Epilepticus and Anton-Babinski Syndrome; Value of ADC Mapping in MELAS
J Neuropsychiatry Clin Neurosci, November 1, 2007; 19(4): 482 - 483.
[Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
A.J. Nemeth, J.W. Henson, M.E. Mullins, R.G. Gonzalez, and P.W. Schaefer
Improved Detection of Skull Metastasis with Diffusion-Weighted MR Imaging
AJNR Am. J. Neuroradiol., June 1, 2007; 28(6): 1088 - 1092.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
N. M. Menezes, S. A. Connolly, F. Shapiro, E. A. Olear, R. M. Jimenez, D. Zurakowski, and D. Jaramillo
Early Ischemia in Growing Piglet Skeleton: MR Diffusion and Perfusion Imaging
Radiology, January 1, 2007; 242(1): 129 - 136.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
P. Summers, P. Staempfli, T. Jaermann, S. Kwiecinski, and S. Kollias
A preliminary study of the effects of trigger timing on diffusion tensor imaging of the human spinal cord.
AJNR Am. J. Neuroradiol., October 1, 2006; 27(9): 1952 - 1961.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
C. S. Rivers, J. M. Wardlaw, P. A. Armitage, M. E. Bastin, T. K. Carpenter, V. Cvoro, P. J. Hand, and M. S. Dennis
Persistent Infarct Hyperintensity on Diffusion-Weighted Imaging Late After Stroke Indicates Heterogeneous, Delayed, Infarct Evolution
Stroke, June 1, 2006; 37(6): 1418 - 1423.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
K. Kono, Y. Okano, K. Nakayama, Y. Hase, S. Minamikawa, N. Ozawa, H. Yokote, and Y. Inoue
Diffusion-weighted MR Imaging in Patients with Phenylketonuria: Relationship between Serum Phenylalanine Levels and ADC Values in Cerebral White Matter
Radiology, August 1, 2005; 236(2): 630 - 636.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
L. Feng, C. L. Dumoulin, S. Dashnaw, R. D. Darrow, R. L. DeLaPaz, P. L. Bishop, and J. Pile-Spellman
Feasibility of Stent Placement in Carotid Arteries with Real-time MR Imaging Guidance in Pigs
Radiology, February 1, 2005; 234(2): 558 - 562.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
S M. Maniega, M E Bastin, P A Armitage, A J Farrall, T K Carpenter, P J Hand, V Cvoro, C S Rivers, and J M Wardlaw
Temporal evolution of water diffusion parameters is different in grey and white matter in human ischaemic stroke
J. Neurol. Neurosurg. Psychiatry, December 1, 2004; 75(12): 1714 - 1718.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
P. Brugieres, P. Thomas, A. Maraval, H. Hosseini, C. Combes, A. Chafiq, L. Ruel, S. Breil, M. Peschanski, and A. Gaston
Water Diffusion Compartmentation at High b Values in Ischemic Human Brain
AJNR Am. J. Neuroradiol., May 1, 2004; 25(5): 692 - 698.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Radiol.Home page
K J Ahn, J W Lee, S T Hahn, D W Yang, P S Kim, H J Kim, and C C Kim
Diffusion-weighted MRI and ADC mapping in FK506 neurotoxicity
Br. J. Radiol., December 1, 2003; 76(912): 916 - 919.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Roentgenol.Home page
N. Sadeghi, I. Camby, S. Goldman, H.-J. Gabius, D. Baleriaux, I. Salmon, C. Decaesteckere, R. Kiss, and T. Metens
Effect of Hydrophilic Components of the Extracellular Matrix on Quantifiable Diffusion-Weighted Imaging of Human Gliomas: Preliminary Results of Correlating Apparent Diffusion Coefficient Values and Hyaluronan Expression Level
Am. J. Roentgenol., July 1, 2003; 181(1): 235 - 241.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
S. Maheshwari and S. K. Mukherji
Diffusion-Weighted Imaging for Differentiating Recurrent Cholesteatoma from Granulation Tissue after Mastoidectomy: Case Report
AJNR Am. J. Neuroradiol., May 1, 2002; 23(5): 847 - 849.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
I.-J. Huang, C.-Y. Chen, H.-W. Chung, D.-C. Chang, C.-C. Lee, S.-C. Chin, and M. Liou
Time Course of Cerebral Infarction in the Middle Cerebral Arterial Territory: Deep Watershed versus Territorial Subtypes on Diffusion-weighted MR Images
Radiology, October 1, 2001; 221(1): 35 - 42.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
L. Reneman, C. B. L. M. Majoie, J. B. A. Habraken, and G. J. den Heeten
Effects of Ecstasy (MDMA) on the Brain in Abstinent Users: Initial Observations with Diffusion and Perfusion MR Imaging
Radiology, September 1, 2001; 220(3): 611 - 617.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
K.-F. Liu, F. Li, T. Tatlisumak, J. H. Garcia, C. H. Sotak, M. Fisher, and J. D. Fenstermacher
Regional Variations in the Apparent Diffusion Coefficient and the Intracellular Distribution of Water in Rat Brain During Acute Focal Ischemia
Stroke, August 1, 2001; 32(8): 1897 - 1905.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
A. Rabinstein, S. Falcone, A. Forteza, and A. Forteza
Diffusion-weighted Imaging Shows Cytotoxic and Vasogenic Edema in Eclampsia
AJNR Am. J. Neuroradiol., June 1, 2001; 22(6): 1068 - 1070.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
M. G. Lansberg, V. N. Thijs, M. W. O'Brien, J. O. Ali, A. J. de Crespigny, D. C. Tong, M. E. Moseley, and G. W. Albers
Evolution of Apparent Diffusion Coefficient, Diffusion-weighted, and T2-weighted Signal Intensity of Acute Stroke
AJNR Am. J. Neuroradiol., April 1, 2001; 22(4): 637 - 644.
[Abstract] [Full Text]

Home page
 Am. J. Neuroradiol.Home page
A. Baur, A. Huber, B. Ertl-Wagner, R. Durr, S. Zysk, S. Arbogast, M. Deimling, and M. Reiser
Diagnostic Value of Increased Diffusion Weighting of a Steady-state Free Precession Sequence for Differentiating Acute Benign Osteoporotic Fractures from Pathologic Vertebral Compression Fractures
AJNR Am. J. Neuroradiol., February 1, 2001; 22(2): 366 - 372.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
C. A. Holder, R. Muthupillai, S. Mukundan Jr, J. D. Eastwood, and P. A. Hudgins
Diffusion-weighted MR Imaging of the Normal Human Spinal Cord in Vivo
AJNR Am. J. Neuroradiol., November 1, 2000; 21(10): 1799 - 1806.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
J. R. Meyer, A. Gutierrez, B. Mock, D. Hebron, J. M. Prager, M. T. Gorey, and D. Homer
High-b-value Diffusion-weighted MR Imaging of Suspected Brain Infarction
AJNR Am. J. Neuroradiol., November 1, 2000; 21(10): 1821 - 1829.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
M. C. DeLano, T. G. Cooper, J. E. Siebert, M. J. Potchen, and K. Kuppusamy
High-b-value Diffusion-weighted MR Imaging of Adult Brain: Image Contrast and Apparent Diffusion Coefficient Map Features
AJNR Am. J. Neuroradiol., November 1, 2000; 21(10): 1830 - 1836.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
P. W. Schaefer, P. E. Grant, and R. G. Gonzalez
Diffusion-weighted MR Imaging of the Brain
Radiology, November 1, 2000; 217(2): 331 - 345.
[Abstract] [Full Text]

Home page
 StrokeHome page
S. L. Keir and J. M. Wardlaw
Systematic Review of Diffusion and Perfusion Imaging in Acute Ischemic Stroke
Stroke, November 1, 2000; 31(11): 2723 - 2731.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
M. Augustin, R. Bammer, J. Simbrunner, R. Stollberger, H.-P. Hartung, and F. Fazekas
Diffusion-weighted Imaging of Patients with Subacute Cerebral Ischemia: Comparison with Conventional and Contrast-enhanced MR Imaging
AJNR Am. J. Neuroradiol., October 1, 2000; 21(9): 1596 - 1602.
[Abstract] [Full Text]

Home page
 J Child NeurolHome page
K. S. Krishnamoorthy, T. B. Soman, M. Takeoka, and P. W. Schaefer
Diffusion-Weighted Imaging in Neonatal Cerebral Infarction: Clinical Utility and Follow-Up
J Child Neurol, September 1, 2000; 15(9): 592 - 602.
[Abstract] [PDF]

Home page
 RadiologyHome page
M. Takahashi, J. Ono, K. Harada, M. Maeda, and D. B. Hackney
Diffusional Anisotropy in Cranial Nerves with Maturation: Quantitative Evaluation with Diffusion MR Imaging in Rats
Radiology, September 1, 2000; 216(3): 881 - 885.
[Abstract] [Full Text]

Home page
 Am. J. Neuroradiol.Home page
R. L. Robertson, S. E. Maier, R. V. Mulkern, S. Vajapayam, C. D. Robson, and P. D. Barnes
MR Line-scan Diffusion Imaging of the Spinal Cord in Children
AJNR Am. J. Neuroradiol., July 1, 2000; 21(7): 1344 - 1348.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
K. H. Lee, S.-J. Cho, H. S. Byun, D. G. Na, N.-C. Choi, S. J. Lee, I.-S. Jin, T. G. Lee, and C.-S. Chung
Triphasic Perfusion Computed Tomography in Acute Middle Cerebral Artery Stroke: A Correlation With Angiographic Findings
Arch Neurol, July 1, 2000; 57(7): 990 - 999.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
R. I. Grossman
BRAIN IMAGING
AJNR Am. J. Neuroradiol., January 1, 2000; 21(1): 9 - 18.
[Full Text] [PDF]

Home page
 StrokeHome page
Q. Yang, B. M. Tress, P. A. Barber, P. M. Desmond, D. G. Darby, R. P. Gerraty, T. Li, and S. M. Davis
Serial Study of Apparent Diffusion Coefficient and Anisotropy in Patients With Acute Stroke
Stroke, November 1, 1999; 30(11): 2382 - 2390.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
A. Y. Liu, J. A. Maldjian, L. J. Bagley, G. P. Sinson, and R. I. Grossman
Traumatic Brain Injury: Diffusion-Weighted MR Imaging Findings
AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1636 - 1641.
[Abstract] [Full Text]

Home page
 Am. J. Neuroradiol.Home page
R. L. Robertson, L. Ben-Sira, P. D. Barnes, R. V. Mulkern, C. D. Robson, S. E. Maier, M. J. Rivkin, and A. J. d. Plessis
MR Line-Scan Diffusion-Weighted Imaging of Term Neonates with Perinatal Brain Ischemia
AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1658 - 1670.
[Abstract] [Full Text]

Home page
 RadiologyHome page
A. G. Sorensen, O. Wu, W. A. Copen, T. L. Davis, R. G. Gonzalez, W. J. Koroshetz, T. G. Reese, B. R. Rosen, V. J. Wedeen, and R. M. Weisskoff
Human Acute Cerebral Ischemia: Detection of Changes in Water Diffusion Anisotropy by Using MR Imaging
Radiology, September 1, 1999; 212(3): 785 - 792.
[Abstract] [Full Text]

Home page
 RadiologyHome page
J. L. Sunshine, R. W. Tarr, C. F. Lanzieri, D. M. D. Landis, W. R. Selman, and J. S. Lewin
Hyperacute Stroke: Ultrafast MR Imaging to Triage Patients prior to Therapy
Radiology, August 1, 1999; 212(2): 325 - 332.
[Abstract] [Full Text]

Home page
 NeurologyHome page
J. W. Hugg, E. J. Butterworth, and R. I. Kuzniecky
Diffusion mapping applied to mesial temporal lobe epilepsy: Preliminary observations
Neurology, July 1, 1999; 53(1): 173 - 173.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Neuroradiol.Home page
A. Arbelaez, M. Castillo, and S. K. Mukherji
Diffusion-Weighted MR Imaging ofGlobal Cerebral Anoxia
AJNR Am. J. Neuroradiol., June 1, 1999; 20(6): 999 - 1007.
[Abstract] [Full Text]

Home page
 RadiologyHome page
R. Bammer, R. Stollberger, M. Augustin, J. Simbrunner, H. Offenbacher, H. Kooijman, S. Ropele, P. Kapeller, P. Wach, F. Ebner, et al.
Diffusion-weighted Imaging with Navigated Interleaved Echo-planar Imaging and a Conventional Gradient System
Radiology, June 1, 1999; 211(3): 799 - 806.
[Abstract] [Full Text]

Home page
 Am. J. Neuroradiol.Home page
R. L. Robertson, S. E. Maier, C. D. Robson, R. V. Mulkern, P. M. Karas, and P. D. Barnes
MR Line Scan Diffusion Imaging of the Brain in Children
AJNR Am. J. Neuroradiol., March 1, 1999; 20(3): 419 - 425.
[Abstract] [Full Text]

Home page
 Am. J. Neuroradiol.Home page
N. Yamada, S. Imakita, and T. Sakuma
Value of Diffusion-Weighted Imaging and Apparent Diffusion Coefficient in Recent Cerebral Infarctions: A Correlative Study with Contrast-Enhanced T1-Weighted Imaging
AJNR Am. J. Neuroradiol., February 1, 1999; 20(2): 193 - 198.
[Abstract] [Full Text]

Home page
 StrokeHome page
L. H. Schwamm, W. J. Koroshetz, A. G. Sorensen, B. Wang, W. A. Copen, R. Budzik, G. Rordorf, F. S. Buonanno, P. W. Schaefer, and R. G. Gonzalez
Time Course of Lesion Development in Patients With Acute Stroke : Serial Diffusion- and Hemodynamic-Weighted Magnetic Resonance Imaging
Stroke, November 1, 1998; 29(11): 2268 - 2276.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
K.J. van Everdingen, J. van der Grond, L.J. Kappelle, L.M.P. Ramos, and W.P.T.M. Mali
Diffusion-Weighted Magnetic Resonance Imaging in Acute Stroke
Stroke, September 1, 1998; 29(9): 1783 - 1790.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
E. L. A. Blezer, M. Schurink, K. Nicolay, P. R. D. Bar, G. H. Jansen, H. A. Koomans, J. A. Joles, and W. G. Mayhan
Proteinuria Precedes Cerebral Edema in Stroke-Prone Rats : A Magnetic Resonance Imaging Study • Editorial Comment: A Magnetic Resonance Imaging Study
Stroke, January 1, 1998; 29(1): 167 - 174.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child.Home page
A Connelly, W K Chong, C L Johnson, V Ganesan, D G Gadian, and F J Kirkham
Diffusion weighted magnetic resonance imaging of compromised tissue in stroke
Arch. Dis. Child., July 1, 1997; 77(1): 38 - 41.
[Abstract] [Full Text]

Home page
 StrokeHome page
P. W. Schaefer, F. S. Buonanno, R. G. Gonzalez, and L. H. Schwamm
Diffusion-Weighted Imaging Discriminates Between Cytotoxic and Vasogenic Edema in a Patient With Eclampsia
Stroke, May 1, 1997; 28(5): 1082 - 1085.
[Abstract] [Full Text]

Home page
 StrokeHome page
K.M.A. Welch, J. Windham, R. A. Knight, V. Nagesh, J. W. Hugg, M. Jacobs, D. Peck, P. Booker, M. O. Dereski, and S. R. Levine
A Model to Predict the Histopathology of Human Stroke Using Diffusion and T2-Weighted Magnetic Resonance Imaging
Stroke, November 1, 1995; 26(11): 1983 - 1989.
[Abstract] [Full Text]


Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X