AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology, Vol 14, Issue 1 119-122, Copyright © 1993 by American Society of Neuroradiology

ARTICLES

Disappearance of cerebral calcification as a sign of tumor growth

S Halpin and D Kingsley
Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, England.

Calcification occurs in many benign and malignant neurologic disorders. We describe two patients with cerebral glioma, in whom the disappearance of cerebral calcification was evidence of local malignant change. We discuss the underlying chemical mechanisms that result in tissue calcification, and postulate that calcification may disappear in the presence of a malignant tumor because of a decrease in the pH of the microenvironment.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X