American Journal of Neuroradiology, Vol 14, Issue 1 227-236, Copyright © 1993 by American Society of Neuroradiology
ARTICLES |
Superficial siderosis of the CNS: MR diagnosis and clinical findings
M Bracchi, M Savoiardo, F Triulzi, D Daniele, M Grisoli, GB Bradac, C Agostinis, D Pelucchetti and G Scotti
Department of Neuroradiology, University of Torino, Italy.
PURPOSE: To report the clinical and neuroradiologic findings of superficial siderosis of the CNS, due to chronic subarachnoid bleeding of unknown origin. MATERIALS AND METHODS: We observed seven cases. The main clinical manifestations were progressive deafness and ataxia. Four patients had had previous cranial or cervical trauma, with root avulsion in two, many years before onset of deafness and ataxia. Neuroradiologic studies included MR (0.5 T in four and 1.5 T in three) and angiography of the brain in all cases, CT in six cases, MR of the spine in six, and myelography in four. RESULTS: MR demonstrated a rim of marked hypointensity in T2-weighted images, consistent with hemosiderin deposits, on the surface of cerebellum, brain stem, inferior part of cerebral hemispheres, and spinal cord. CT showed cerebellar atrophy in five cases, and a rim of mild hyperdensity around the brain stem in two. Angiographic studies were negative. Myelography showed cervical nerve root avulsion in two cases and a cervicodorsal extradural cyst in one. Cerebrospinal fluid contained RBCs in all the six examined cases. CONCLUSION: Although CT may occasionally suggest the diagnosis of superficial siderosis, MR demonstrates this abnormality to better advantage.
This article has been cited by other articles:
 |
|
 |
|
  J. Le Scanff, A. Vighetto, C. Gedeon, M. Bonnefoy, and P. Krolak-Salmon Superficial Siderosis Revealed by Isolated Cognitive Impairment J Gerontol A Biol Sci Med Sci, March 1, 2009; 64A(3): 385 - 387. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Kumar Superficial Siderosis: Associations and Therapeutic Implications Arch Neurol, April 1, 2007; 64(4): 491 - 496. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Savoiardo, E. Maccagnano, D. Pareyson, M. Grisoli, and N. Kumar Superficial siderosis Neurology, February 20, 2007; 68(8): 623 - 624. [Full Text] [PDF]
|
|
|
|
|
|
N. Kumar, A. A. Cohen-Gadol, R. A. Wright, G. M. Miller, D. G. Piepgras, and J. E. Ahlskog Superficial siderosis Neurology, April 25, 2006; 66(8): 1144 - 1152. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Grisoli, A. Piperno, L. Chiapparini, R. Mariani, and M. Savoiardo MR Imaging of Cerebral Cortical Involvement in Aceruloplasminemia AJNR Am. J. Neuroradiol., March 1, 2005; 26(3): 657 - 661. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A Messori, P Di Bella, N Herber, F Logullo, M Ruggiero, and U Salvolini The importance of suspecting superficial siderosis of the central nervous system in clinical practice J. Neurol. Neurosurg. Psychiatry, February 1, 2004; 75(2): 188 - 190. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B Turner and A J Wills Superficial siderosis associated with anterior horn cell dysfunction J. Neurol. Neurosurg. Psychiatry, February 1, 2002; 72(2): 274 - 275. [Full Text] [PDF]
|
|
|
|
|
|
M. Mascalchi, F. Salvi, M. G. Pirini, A. D'Errico, A. Ferlini, F. Lolli, R. Plasmati, C. Tessa, N. Villari, and C. A. Tassinari Transthyretin amyloidosis and superficial siderosis of the CNS Neurology, October 22, 1999; 53(7): 1498 - 1498. [Abstract] [Full Text]
|
|
|
|
|
|
W. C. Hsu, L. A. Loevner, M. S. Forman, and E. R. Thaler Superficial Siderosis of the CNS Associated with Multiple Cavernous Malformations AJNR Am. J. Neuroradiol., August 1, 1999; 20(7): 1245 - 1248. [Abstract] [Full Text]
|
|
|
|
|
|
N. E. Anderson, S. Sheffield, and J. K. A. Hope Superficial siderosis of the central nervous system: A late complication of cerebellar tumors Neurology, January 1, 1999; 52(1): 163 - 163. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. H. O'Leary and S. de la Monte Case 2-1998- A 50-Year-Old Woman with Increasing Headache and a Left Abducent-Nerve Palsy N. Engl. J. Med., January 15, 1998; 338(3): 180 - 188. [Full Text] [PDF]
|
|