American Journal of Neuroradiology, Vol 16, Issue 6 1307-1311, Copyright © 1995 by American Society of Neuroradiology
ARTICLES |
Effect of disk maturation on diffusion of low-molecular-weight gadolinium complexes: an experimental study in rabbits
MA Ibrahim, VM Haughton and JS Hyde
Department of Radiology, Medical College of Wisconsin, Milwaukee 53226, USA.
PURPOSE: To measure the rate of enhancement in immature intervertebral disks in comparison with that of mature disks after intravenous administration of gadolinium-containing contrast media. METHODS: Four rabbits were imaged with MR for 120 minutes after the injection of gadopentetate dimeglumine, gadoteridol, or gadodiamide. Contrast enhancement was measured in the lumbar intervertebral disks on each image. The rate and magnitude of enhancement in the immature and mature disks were compared. RESULTS: Contrast enhancement was detected in intervertebral disks with all three contrast media. Enhancement was significantly greater in immature than in mature animals. CONCLUSION: Greater enhancement in immature disks is consistent with a lower concentration of fixed negative charges in the glycosaminoglycans of the disk.
This article has been cited by other articles:
 |
|
 |
|
  M. T. Modic and J. S. Ross Lumbar Degenerative Disk Disease Radiology, October 1, 2007; 245(1): 43 - 61. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Haughton Imaging Intervertebral Disc Degeneration J. Bone Joint Surg. Am., April 1, 2006; 88(suppl_2): 15 - 20. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Grunhagen, G. Wilde, D. M. Soukane, S. A. Shirazi-Adl, and J. P.G. Urban Nutrient Supply and Intervertebral Disc Metabolism J. Bone Joint Surg. Am., April 1, 2006; 88(suppl_2): 30 - 35. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.-S. Hsu, G.-C. Liu, S.-H. Chen, T.-S. Jaw, W.-J. Shen, and C.-Y. Chen Ionic versus Nonionic Paramagnetic Contrast Media in Differentiating between Postoperative Scar and Recurrent Disk AJNR Am. J. Neuroradiol., June 1, 2004; 25(6): 1110 - 1115. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Haughton, K. Schreibman, and A. De Smet Contrast between Scar and Recurrent Herniated Disk on Contrast-Enhanced MR Images AJNR Am. J. Neuroradiol., November 1, 2002; 23(10): 1652 - 1656. [Abstract] [Full Text] [PDF]
|
|