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American Journal of Neuroradiology, Vol 17, Issue 4 773-776, Copyright © 1996 by American Society of Neuroradiology


ARTICLES

Contrast-enhanced magnetization transfer saturation imaging improves MR detection of herpes simplex encephalitis

JW Burke, VP Mathews, AD Elster, JL Ulmer, FM McLean and SB Davis
Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157, USA.

Cranial MR imaging was performed in three patients in whom herpes simplex encephalitis was subsequently proved. In all cases, the postcontrast T1 weighted MR images obtained with magnetization transfer saturation showed greater central nervous system involvement than was apparent on the conventional MR images. Specifically, the postcontrast magnetization transfer images were superior at delineating generalized meningeal enhancement as well as focal areas of brain involvement not seen on noncontrast T2-weighted images orconventionalpostcontrast T1- weightedimages.


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