American Journal of Neuroradiology, Vol 18, Issue 10 1905-1908, Copyright © 1997 by American Society of Neuroradiology
ARTICLES |
Paradoxical hyperfixation of hexamethylpropyleneamine oxime in cerebral infarction
S Shintani, S Tsuruoka and T Shiigai
Department of Neurology, Toride Kyodo General Hospital, Toride City, Ibaraki, Japan.
We describe four patients with cerebral infarction and 99mTc- hexamethylpropyleneamine oxime (HMPAO) hyperfixation in distributions corresponding to the infarctions seen at CT and/or MR imaging. Increased HMPAO extraction due to hyperpermeability across the blood- brain barrier and increased retention due to reduced back diffusion of the tracer probably accounted for the increased fractional fixation in infarcts seen in our patients.
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