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American Journal of Neuroradiology, Vol 18, Issue 3 533-535, Copyright © 1997 by American Society of Neuroradiology


ARTICLES

Proton MR spectroscopy in Pelizaeus-Merzbacher disease

J Takanashi, K Sugita, H Osaka, M Ishii and H Niimi
Department of Pediatrics, Faculty of Medicine, University of Chiba, Japan.

Proton MR spectroscopic findings in two patients with genetically defined Pelizaeus-Merzbacher disease revealed ratios of N- acetylaspartate/creatine and choline-containing compounds/creatine that were not significantly different from those found in a population of healthy subjects. These findings suggest that proton MR spectroscopy can aid in the diagnosis of Pelizaeus-Merzbacher disease.


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